Way back in 2005, in Can Caffeine Brain Boost Help Ad Recall?, I suggested that Starbucks could sell potent ads on their cups. This idea, though tongue-in-cheek in nature, was based on fMRI research that showed caffeine stimulated areas of the brain associated with memory:
Dr Florian Koppelstatter of the Medical University Innsbruck, Austria, found that caffeine affects distinct areas of the brain. This study is beleived to be the first to demonstrate a visible impact on the brain from caffeine. Subjects who had been given caffeine showed significantly more activity in the frontal lobe and the anterior cingulum – areas of the brain associated with memory and attention. Subjects who received a placebo showed no such impact.